Purging of highly deleterious mutations through severe bottlenecks in Alpine ibex
نویسندگان
چکیده
منابع مشابه
Mistranslation can enhance fitness through purging of deleterious mutations
Phenotypic mutations are amino acid changes caused by mistranslation. How phenotypic mutations affect the adaptive evolution of new protein functions is unknown. Here we evolve the antibiotic resistance protein TEM-1 towards resistance on the antibiotic cefotaxime in an Escherichia coli strain with a high mistranslation rate. TEM-1 populations evolved in such strains endow host cells with a gen...
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In the early 2000s, several colonies of Alpine ibex (Capra ibex ibex) in Switzerland ceased growing or began to decrease. Reproductive problems due to infections with abortive agents might have negatively affected recruitment. We assessed the presence of selected agents of abortion in Alpine ibex by serologic, molecular, and culture techniques and evaluated whether infection with these agents m...
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In prey species, vigilance is an important behavioural trait with regard to antipredator strategies. It has been studied intensely in animals. However, lile is known about vigilance in animal kids. In this study, I investigated the inuence of various environmental and social factors on Alpine ibex (Capra ibex) and Alpine chamois (Rupicapra rupicapra) kid vigilance behaviour. In the Gran Parad...
متن کاملThe evolution of selfing is accompanied by reduced efficacy of selection and purging of deleterious mutations.
The transition from outcrossing to selfing is predicted to reduce the genome-wide efficacy of selection because of the lower effective population size (Ne) that accompanies this change in mating system. However, strongly recessive deleterious mutations exposed in the homozygous backgrounds of selfers should be under strong purifying selection. Here, we examine estimates of the distribution of f...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2020
ISSN: 2041-1723
DOI: 10.1038/s41467-020-14803-1